|
|
S-formylglutathione + H2O <=> H+ + formate + glutathione
|
3.1.1.56
methylumbelliferyl-acetate deacetylase
3.1.2.12
S-formylglutathione hydrolase
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
–
–
|
BMK
|
|
BRENDA:
BR10672
KEGG:
R00527
MetaCyc:
S-FORMYLGLUTATHIONE-HYDROLASE-RXN
SABIO-RK:
945
|
|
|
|
H2O + S-succinylglutathione <=> H+ + succinate + glutathione
|
3.1.2.13
S-succinylglutathione hydrolase
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
–
|
|
|
BRENDA:
BR10673
KEGG:
R00499
MetaCyc:
S-SUCCINYLGLUTATHIONE-HYDROLASE-RXN
SABIO-RK:
929
|
|
|
|
S-acylglutathione + H2O <=> a_carboxylate + glutathione + H+
|
3.1.2.7
glutathione thiolesterase
|
–
|
|
|
BRENDA:
BR10677
KEGG:
R00547
MetaCyc:
GLUTATHIONE-THIOESTERASE-RXN
|
|
|
|
glycine + gamma-Glu-L-Cys + ATP <=> glutathione + ADP + phosphate + H+
|
6.3.2.3
glutathione synthase
|
–
|
BMK
|
|
BRENDA:
BR119
KEGG:
R00497
MetaCyc:
GLUTATHIONE-SYN-RXN
SABIO-RK:
927
|
|
|
|
S-(2-hydroxyacyl)glutathione + H2O <=> glutathione + alpha-hydroxy_acid + H+
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BR15913
KEGG:
R04090
MetaCyc:
RXN-7919
|
|
|
|
glutathione + methylarsonate + H+ <=> GSSG + methylarsonite + H2O
|
1.20.4.2
methylarsonate reductase
|
–
|
|
|
BRENDA:
BR29383
KEGG:
R05748
MetaCyc:
1.20.4.2-RXN
|
|
|
|
H+ + sulfite + AMP + GSSG <=> adenosine_5''-phosphosulfate + glutathione
|
1.8.4.10
adenylyl-sulfate reductase (thioredoxin)
1.8.4.9
adenylyl-sulfate reductase (glutathione)
1.8.99.2
adenylyl-sulfate reductase
|
–
–
–
|
BMK
|
|
BRENDA:
BR29461
KEGG:
R05717
MetaCyc:
1.8.4.9-RXN
SABIO-RK:
5311
|
|
|
|
glutathionylspermidine + H2O <=> glutathione + spermidine
|
3.5.1
3.5.1.78
glutathionylspermidine amidase
|
–
–
|
K
|
|
BRENDA:
BR3215
KEGG:
R01918
MetaCyc:
GSPAMID-RXN
SABIO-RK:
1972
|
|
|
|
dehydroascorbate + glutathione <=> ascorbate + GSSG
|
1.8.4.9
adenylyl-sulfate reductase (glutathione)
1.8.5.1
glutathione dehydrogenase (ascorbate)
|
–
–
|
MK
|
|
BRENDA:
BR36971
KEGG:
R01108
MetaCyc:
1.8.5.1-RXN
SABIO-RK:
1372
|
|
|
|
glutathione + NADP+ <=> GSSG + NADPH + H+
|
1.8.1.7
glutathione-disulfide reductase
1.8.1.9
thioredoxin-disulfide reductase
1.8.1.B1
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR37011
KEGG:
R00115
MetaCyc:
GLUTATHIONE-REDUCT-NADPH-RXN
SABIO-RK:
695
|
|
|
|
glutathione + hydroperoxy-fatty-acyl-[lipid] <=> GSSG + a_hydroxy-fatty-acyl-[lipid] + H2O
|
1.11.1.12
phospholipid-hydroperoxide glutathione peroxidase
|
–
|
M
|
|
BRENDA:
BR37014
MetaCyc:
1.11.1.12-RXN
|
|
|
|
O2 + glutathione <=> GSSG + H2O2
|
1.8.3.2
thiol oxidase
1.8.3.3
glutathione oxidase
|
–
–
|
K
|
|
BRENDA:
BR37015
KEGG:
R00120
MetaCyc:
GLUTATHIONE-OXIDASE-RXN
|
|
|
|
GSSG + CoA <=> glutathione + CoA-glutathione
|
1.8.4.3
glutathione---CoA-glutathione transhydrogenase
|
–
|
K
|
|
BRENDA:
BR37024
KEGG:
R01111
MetaCyc:
1.8.4.3-RXN
|
|
|
|
L-cystine + glutathione <=> GSSG + L-cysteine
|
1.8.1.6
cystine reductase
1.8.4.4
glutathione---cystine transhydrogenase
1.8.4.9
adenylyl-sulfate reductase (glutathione)
|
–
–
–
|
BK
|
|
BRENDA:
BR37026
KEGG:
R01109;
R01113
MetaCyc:
1.8.4.4-RXN
|
|
|
|
glutathione + CoA + NADP+ <=> H+ + CoA-glutathione + NADPH
|
1.8.1.10
CoA-glutathione reductase
1.8.1.14
CoA-disulfide reductase
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
–
–
|
|
|
BRENDA:
BR37037
KEGG:
R05714
MetaCyc:
COA-GLUTATHIONE-REDUCTASE-NADPH-RXN
SABIO-RK:
5308
|
|
|
|
glutathione + H2O2 <=> GSSG + H2O
|
1.11.1.27
glutathione-dependent peroxiredoxin
1.11.1.9
glutathione peroxidase
|
–
–
|
MK
|
|
BRENDA:
BR37185
KEGG:
R00274
MetaCyc:
GLUTATHIONE-PEROXIDASE-RXN
SABIO-RK:
376
|
|
|
|
pyrimidodiazepine + GSSG + H2O <=> 6-pyruvoyltetrahydropterin + glutathione
|
1.5.4.1
pyrimidodiazepine synthase
|
–
|
MK
|
|
BRENDA:
BR40353
KEGG:
R03984
MetaCyc:
1.5.4.1-RXN
|
|
|
|
S-sulfanylglutathione + O2 + H2O <=> glutathione + sulfite + H+
|
1.13.11.18
persulfide dioxygenase
|
–
|
K
|
|
BRENDA:
BR40486
KEGG:
R08678
MetaCyc:
RXN-13161
SABIO-RK:
15159
|
|
|
|
leukotriene_C4 <=> leukotriene_A4 + glutathione
|
4.4.1.20
leukotriene-C4 synthase
|
–
|
BMK
|
|
BRENDA:
BR48007
KEGG:
R03059
MetaCyc:
LEUKOTRIENE-C4-SYNTHASE-RXN
SABIO-RK:
8569
|
|
|
|
thiosulfate + glutathione <=> H+ + sulfite + Sulfide + GSSG
|
2.8.1.3
thiosulfate---thiol sulfurtransferase
|
–
|
K
|
|
BRENDA:
BR48101
KEGG:
R01875
MetaCyc:
THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN
|
|
|
|
S-hydroxymethylglutathione <=> formaldehyde + glutathione
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
4.4.1.22
S-(hydroxymethyl)glutathione synthase
|
–
–
|
BMK
|
|
BRENDA:
BR48540
KEGG:
R06982
MetaCyc:
RXN-2961
SABIO-RK:
7488
|
|
|
|
glutathione + glutathionylspermidine + ATP <=> H+ + trypanothione + ADP + phosphate
|
6.3.1.9
trypanothione synthase
|
–
|
BMK
|
|
BRENDA:
BR48737;
BS427492
KEGG:
R03822
MetaCyc:
6.3.1.9-RXN
SABIO-RK:
3578
|
|
|
|
S-sulfinatoglutathione + H2O <=> glutathione + sulfite + H+
|
1.13.11.18
persulfide dioxygenase
|
–
|
M
|
|
BRENDA:
BR49515
KEGG:
R11947
MetaCyc:
RXN-16574
|
|
|
|
glutathione + H2O <=> Cys-Gly + L-glutamate
|
2.3.2.2
gamma-glutamyltransferase
3.4.19.13
glutathione gamma-glutamate hydrolase
3.5.1.93
glutaryl-7-aminocephalosporanic-acid acylase
|
–
–
–
|
BMK
|
|
BRENDA:
BR49838
KEGG:
R00494
MetaCyc:
RXN-12618
SABIO-RK:
926
|
|
|
|
2-(glutathione-S-yl)-2-methylbut-3-en-1-ol <=> (3R)-3,4-epoxy-3-methylbut-1-ene + glutathione
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
M
|
|
BRENDA:
BR51784
KEGG:
R11411
MetaCyc:
RXN-17592
|
|
|
|
1-aci-nitro-2-phenylethane + glutathione <=> S-[(Z)-N-hydroxy(phenyl)acetimidoyl]-L-glutathione + H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
M
|
|
BRENDA:
BR52041
KEGG:
R11739
MetaCyc:
RXN-11420
|
|
|
|
glutathione <=> Cys-Gly + 5-oxoproline
|
4.3.2.7
glutathione-specific gamma-glutamylcyclotransferase
4.3.2.9
gamma-glutamylcyclotransferase
|
–
–
|
MK
|
|
BRENDA:
BR52222
KEGG:
R11861
MetaCyc:
RXN-19024
SABIO-RK:
15394
|
|
|
|
2,6-dichlorohydroquinone + Cl- + GSSG + H+ <=> 2,3,5-trichlorohydroquinone + glutathione
|
1.21.4.5
tetrachlorohydroquinone reductive dehalogenase
|
–
|
K
|
|
BRENDA:
BR52571
KEGG:
R05403
MetaCyc:
TECH2REDHAL-RXN
|
|
|
|
2,3,5-trichlorohydroquinone + Cl- + GSSG <=> tetrachlorohydroquinone + glutathione
|
1.21.4.5
tetrachlorohydroquinone reductive dehalogenase
|
–
|
K
|
|
BRENDA:
BR52572
KEGG:
R05402
MetaCyc:
TECH1REDHAL-RXN
|
|
|
|
glutathione + ROOH <=> GSSG + H2O + an_alcohol
|
1.11.1.27
glutathione-dependent peroxiredoxin
1.11.1.9
glutathione peroxidase
|
–
–
|
K
|
|
BRENDA:
BR53022
KEGG:
R12578
MetaCyc:
RXN-20693
|
|
|
|
S-D-lactoylglutathione <=> methylglyoxal + glutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
BMK
|
|
BRENDA:
BR6441
KEGG:
R02530
MetaCyc:
GLYOXI-RXN
SABIO-RK:
177
|
|
|
|
spermidine + glutathione + ATP <=> H+ + glutathionylspermidine + ADP + phosphate
|
6.3.1.8
glutathionylspermidine synthase
6.3.1.9
trypanothione synthase
|
–
–
|
BMK
|
|
BRENDA:
BR99
KEGG:
R01917
MetaCyc:
GSPSYN-RXN
SABIO-RK:
1971
|
|
|
|
glutathione + ATP + H2O <=> glutathione + ADP + phosphate + H+
|
3.6.3.M9
7.2.2.2
ABC-type Cd2+ transporter
7.4.2.10
ABC-type glutathione transporter
7.4.2.6
ABC-type oligopeptide transporter
7.6.2.2
ABC-type xenobiotic transporter
7.6.2.3
ABC-type glutathione-S-conjugate transporter
|
–
–
–
–
–
–
|
|
|
BRENDA:
BS141495
MetaCyc:
RXN0-11;
RXN0-21
|
|
|
|
D-Cystine + glutathione <=> GSSG + D-cysteine
|
1.8.4.4
glutathione---cystine transhydrogenase
|
–
|
|
|
BRENDA:
BS260606
MetaCyc:
RXN-14497
|
|
|
|
1-chloro-2,4-dinitrobenzene + glutathione <=> H+ + S-(2,4-dinitrophenyl)glutathione + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS354742
MetaCyc:
GST-RXN
SABIO-RK:
6622
|
|
|
|
S-D-lactoylglutathione + H2O <=> H+ + glutathione + D-lactate
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
BMK
|
|
BRENDA:
BS364477
KEGG:
R01736
MetaCyc:
GLYOXII-RXN
SABIO-RK:
283
|
|
|
|
glutathione + (+/-)-2-bromo-3-(4-nitrophenyl)propionic_acid <=> 2-(glutathion-S-yl)-3-(4-nitrophenyl)propanoic_acid + Br- + H+
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS378765
MetaCyc:
RXN-19610
|
|
|
|
glutathione + Gly-Gly <=> 5-L-glutamyl-Gly-Gly + Cys-Gly
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS388816
MetaCyc:
RXN-18092
|
|
|
|
glutathione + 4-hydroxy-2-nonenal <=> S-(4-hydroxy-1-oxononan-3-yl)glutathione
|
2.5.1.18
glutathione transferase
|
–
|
M
|
|
BRENDA:
BS407314
MetaCyc:
RXN-13673
|
|
|
|
glutathione + hypoglycin <=> hypoglycin_B + Cys-Gly
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
M
|
|
BRENDA:
BS423687
MetaCyc:
RXN-9157
|
|
|
|
glutathione + monochlorobimane <=> GS-bimane + Cl- + H+
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS423867
MetaCyc:
RXN-19573
|
|
|
|
3-(glutathione-S-yl)-2,6-dichloro-p-hydroquinone + glutathione <=> H+ + 2,6-dichlorohydroquinone + GSSG
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
M
|
|
BRENDA:
BS439570
MetaCyc:
RXN-18403
|
|
|
|
2-(glutathione-S-yl)-trichloro-p-hydroquinone + glutathione <=> 2,3,5-trichlorohydroquinone + GSSG + H+
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
M
|
|
BRENDA:
BS439577
MetaCyc:
RXN-18406
|
|
|
|
glutathione + Dichloroacetate <=> 2-(glutathion-S-yl)-chloroacetate + Cl- + H+
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS445444
MetaCyc:
RXN-19611
|
|
|
|
[Xanthine_dehydrogenase] + GSSG <=> [xanthine_oxidase] + 2 glutathione
|
1.8.4.7
enzyme-thiol transhydrogenase (glutathione-disulfide)
|
–
|
K
|
|
BRENDA:
BR37007
KEGG:
R04039
|
|
|
|
2 glutathione + protein_disulfide <=> GSSG + protein-dithiol
|
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
|
K
|
|
BRENDA:
BR37013
KEGG:
R03915
|
|
|
|
L-homocystine + glutathione <=> GSSG + L-homocysteine
|
1.8.4.1
glutathione---homocystine transhydrogenase
|
–
|
K
|
|
BRENDA:
BR37027
KEGG:
R01110;
R01292
MetaCyc:
1.8.4.1-RXN
|
|
|
|
glutathione + [Glu(-Cys)]n-Gly <=> glycine + [Glu(-Cys)]n+1-Gly
|
2.3.2.15
glutathione gamma-glutamylcysteinyltransferase
|
–
|
|
|
BRENDA:
BR44109
KEGG:
R03956
SABIO-RK:
3695
|
|
|
|
RX + glutathione <=> acceptor + R-S-glutathione
|
2.5.1.18
glutathione transferase
2.5.1.75
tRNA dimethylallyltransferase
|
–
–
|
BK
|
|
BRENDA:
BR47501
KEGG:
R03522
SABIO-RK:
3310
|
|
|
|
2-(glutathione-S-yl)-hydroquinone + glutathione <=> hydroquinone + GSSG
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BR51930
KEGG:
R11659
MetaCyc:
RXN-18402
|
|
|
|
an_omega-(methylthio)-(E)-alkanal_oxime + reduced_flavodoxin + glutathione + O2 <=> (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate + flavin + 2 H2O
|
1.14.14.40
phenylalanine N-monooxygenase
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
–
–
|
|
|
BRENDA:
BR51951;
BS438185
KEGG:
R11650
|
|
|
|
a_1-aci-nitro-omega-(methylthio)alkane + glutathione <=> (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
M
|
|
BRENDA:
BR51953
KEGG:
R11652
MetaCyc:
RXN-11422
|
|
|
|
1-aci-nitro-2-indolyl-ethane + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine + H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
M
|
|
BRENDA:
BR52038
KEGG:
R11736
MetaCyc:
RXN-11421
|
|
|
|
(E)-phenylacetaldoxime + reduced_flavodoxin + glutathione + O2 <=> S-[(Z)-N-hydroxy(phenyl)acetimidoyl]-L-glutathione + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BR52039
KEGG:
R11737
|
|
|
|
Sulfide + glutathione + a_quinone <=> S-sulfanylglutathione + a_quinol
|
1.8.5.8
eukaryotic sulfide quinone oxidoreductase
|
–
|
K
|
|
BRENDA:
BR52238
KEGG:
R11929
|
|
|
|
glutathione + lipid_hydroperoxide <=> GSSG + Lipid + H2O
|
1.11.1.12
phospholipid-hydroperoxide glutathione peroxidase
|
–
|
K
|
|
BRENDA:
BS260442;
BS402670
KEGG:
R03167
|
|
|
|
trypanothione + H2O <=> glutathione + glutathionylspermidine
|
3.5.1
3.5.1.78
glutathionylspermidine amidase
|
–
–
|
K
|
|
BRENDA:
BS367840
KEGG:
R08350
|
|
|
|
GSSG + NADH + H+ <=> 2 glutathione + NAD+
|
1.8.1.16
glutathione amide reductase
1.8.1.7
glutathione-disulfide reductase
|
–
–
|
|
|
BRENDA:
BS388832
KEGG:
R00094
SABIO-RK:
676
|
|
|
|
H+ + S-Glutathionyl-L-cysteine + NADPH <=> L-cysteine + glutathione + NADP+
|
1.8.1.10
CoA-glutathione reductase
1.8.1.9
thioredoxin-disulfide reductase
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
–
–
|
K
|
|
KEGG:
R00900
MetaCyc:
GSCYSDEG-RXN
SABIO-RK:
1222
|
|
|
|
2,5-dichloro-p-quinol + glutathione <=> H+ + chlorohydroquinone + GSSG + Cl-
|
2.5.1
|
–
|
MK
|
|
KEGG:
R05269
MetaCyc:
LIND-RXN
|
|
|
|
Cl- + hydroquinone + GSSG + H+ <=> chlorohydroquinone + glutathione
|
2.5.1
|
–
|
K
|
|
KEGG:
R05267
MetaCyc:
RXN-12506
|
|
|
|
Selenite + glutathione + H+ <=> Selenodiglutathione + GSSG + H2O
|
not assigned
|
–
|
MK
|
|
KEGG:
R09367
MetaCyc:
RXN-12864
|
|
|
|
formaldehyde + glutathione + NAD+ <=> S-formylglutathione + NADH + H+
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS189060
SABIO-RK:
161
|
|
|
|
methylglyoxal + glutathione + NAD+ <=> S-pyruvylglutathione + NADH
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS189072
SABIO-RK:
12381
|
|
|
|
tert-butyl_hydroperoxide + 2 glutathione <=> tert-butanol + GSSG + H2O
|
1.11.1.27
glutathione-dependent peroxiredoxin
1.11.1.9
glutathione peroxidase
|
–
–
|
|
|
BRENDA:
BS261209
SABIO-RK:
10590
|
|
|
|
cumene_hydroperoxide + 2 glutathione <=> 2-phenylpropan-2-ol + GSSG + H2O
|
1.11.1.27
glutathione-dependent peroxiredoxin
1.11.1.9
glutathione peroxidase
2.5.1.18
glutathione transferase
5.3.99.2
prostaglandin-D synthase
5.3.99.3
prostaglandin-E synthase
|
–
–
–
–
–
|
|
|
BRENDA:
BS368753
SABIO-RK:
10575
|
|
|
|
15-hydroperoxy-prostaglandin_E2 + glutathione <=> prostaglandin_E2 + GSSG
|
1.11.1.9
glutathione peroxidase
5.3.99.3
prostaglandin-E synthase
|
–
–
|
|
|
BRENDA:
BS368755
SABIO-RK:
14117
|
|
|
|
2,4-dinitro-1-iodobenzene + glutathione <=> S-(2,4-dinitrophenyl)glutathione + I-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS378889
SABIO-RK:
13497
|
|
|
|
S-Lactoylglutathione + H2O <=> D-lactate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS382777
SABIO-RK:
10510
|
|
|
|
S-propionylglutathione + H2O <=> glutathione + propionate
|
3.1.2.6
hydroxyacylglutathione hydrolase
3.1.2.7
glutathione thiolesterase
|
–
–
|
|
|
BRENDA:
BS382786
SABIO-RK:
10941
|
|
|
|
1,2-dichloro-4-nitrobenzene + glutathione <=> S-(2-chloro-4-nitro-phenyl)glutathione + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS407697
SABIO-RK:
12846
|
|
|
|
1-bromo-2,4-dinitrobenzene + glutathione <=> S-(2,4-dinitrophenyl)glutathione + Br-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS422252
SABIO-RK:
13496
|
|
|
|
1-Fluoro-2,4-dinitrobenzene + glutathione <=> S-(2,4-dinitrophenyl)glutathione + F-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS422259
SABIO-RK:
6621
|
|
|
|
S-acetylglutathione + H2O <=> glutathione + acetate
|
3.1.2.12
S-formylglutathione hydrolase
3.1.2.6
hydroxyacylglutathione hydrolase
3.1.2.7
glutathione thiolesterase
|
–
–
–
|
|
|
BRENDA:
BS64573
SABIO-RK:
10454
|
|
|
|
S-Acetoacetylglutathione + H2O <=> acetoacetate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS93046
SABIO-RK:
10436
|
|
|
|
S-(beta-ethoxy-alpha-D-hydroxybutyryl)glutathione + H2O <=> beta-ethoxy-alpha-D-hydroxybutyrate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS93052
SABIO-RK:
10938
|
|
|
|
2-hydroxyethyl_disulfide + glutathione <=> 2-mercaptoethanol + GSSG
|
1.8.4.2
protein-disulfide reductase (glutathione)
2.5.1.18
glutathione transferase
|
–
–
|
|
|
MetaCyc:
RXN0-6256
SABIO-RK:
10291
|
|
|
|
Bromoacetate + glutathione <=> H+ + 2-S-Glutathionyl_acetate + Br-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
MetaCyc:
RXN0-6549
SABIO-RK:
14987
|
|
|
|
2 glutathione + (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate <=> GSSG + 5-hydroxyeicosatetraenoic_acid + H2O
|
1.11.1.9
glutathione peroxidase
|
–
|
K
|
|
KEGG:
R07034
SABIO-RK:
7538
|
|
|
|
glutathione + an_L-amino_acid <=> Cys-Gly + 5-L-glutamyl-L-amino_acid
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
K
|
|
KEGG:
R01262
|
|
|
|
Insulin + 2 glutathione <=> reduced_insulin + GSSG
|
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
|
K
|
|
KEGG:
R02824
|
|
|
|
D-Lactaldehyde + glutathione + NAD+ <=> S-D-lactoylglutathione + NADH + H+
|
not assigned
|
–
|
|
|
KEGG:
R03082
|
|
|
|
S-Glutathionyl-L-cysteine + sulfate <=> S-sulfocysteine + glutathione
|
1.8.4.3
glutathione---CoA-glutathione transhydrogenase
|
–
|
K
|
|
KEGG:
R04860
|
|
|
|
(1R,2S)-Naphthalene_1,2-oxide + glutathione <=> (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07002
|
|
|
|
(1S,2R)-Naphthalene_1,2-oxide + glutathione <=> (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07003
|
|
|
|
(1S,2R)-Naphthalene_1,2-oxide + glutathione <=> (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07004
|
|
|
|
1-Nitronaphthalene-7,8-oxide + glutathione <=> 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07023
|
|
|
|
1-Nitronaphthalene-7,8-oxide + glutathione <=> 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07024
|
|
|
|
1-Nitronaphthalene-5,6-oxide + glutathione <=> 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07025
|
|
|
|
1-Nitronaphthalene-5,6-oxide + glutathione <=> 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07026
|
|
|
|
2 glutathione + 15-hydroperoxyeicosatetraenoic_acid <=> GSSG + (15S)-hydroxyeicosatetraenoic_acid + H2O
|
1.11.1.9
glutathione peroxidase
|
–
|
K
|
|
KEGG:
R07035
|
|
|
|
Bromobenzene-3,4-oxide + glutathione <=> 3,4-Dihydro-3-hydroxy-4-S-glutathionyl_bromobenzene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07069
|
|
|
|
Bromobenzene-2,3-oxide + glutathione <=> 2,3-Dihydro-2-S-glutathionyl-3-hydroxy_bromobenzene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07070
|
|
|
|
benzopyrene_4,5-oxide + glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07083
|
|
|
|
benzo(a)pyrene-7,8-diol + glutathione <=> 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene + H2O
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07084
|
|
|
|
2,2-Dichloroacetaldehyde + glutathione <=> S-(2,2-Dichloro-1-hydroxy)ethyl_glutathione
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07091
|
|
|
|
1,1-Dichloroethylene_epoxide + glutathione <=> 2-(S-Glutathionyl)acetyl_chloride + Hydrochloric_acid
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07092
|
|
|
|
Chloroacetyl_chloride + glutathione <=> S-(2-Chloroacetyl)glutathione + Hydrochloric_acid
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07093
|
|
|
|
2-(S-Glutathionyl)acetyl_chloride + glutathione <=> 2-(S-Glutathionyl)acetyl_glutathione + Hydrochloric_acid
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07094
|
|
|
|
Trichloroethylene + glutathione <=> S-(1,2-Dichlorovinyl)glutathione + Hydrochloric_acid
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07100
|
|
|
|
1,2-Dibromoethane + glutathione + H+ <=> Glutathione_episulfonium_ion + 2 Hydrobromic_acid
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07113
|
|
|
|
bromoacetaldehyde + glutathione <=> S-(Formylmethyl)glutathione + Hydrobromic_acid
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R07116
|
|
|
|
2-(S-Glutathionyl)acetyl_glutathione + H2O <=> 2-S-Glutathionyl_acetate + glutathione
|
not assigned
|
–
|
K
|
|
KEGG:
R07124
|
|
|
|
aldophosphamide + glutathione <=> 4-Glutathionyl_cyclophosphamide + H2O
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R08280
|
|
|
|
Homotrypanothione + H2O <=> glutathione + Glutathionylaminopropylcadaverine
|
3.5.1
|
–
|
K
|
|
KEGG:
R08351
|
|
|
|
ATP + glutathione + spermine <=> ADP + phosphate + Glutathionylspermine
|
6.3.1.9
trypanothione synthase
|
–
|
K
|
|
KEGG:
R08352
|
|
|
|
ATP + glutathione + Glutathionylspermine <=> ADP + phosphate + Bis(glutathionyl)spermine
|
6.3.1.9
trypanothione synthase
|
–
|
K
|
|
KEGG:
R08353
|
|
|
|
ATP + glutathione + aminopropylcadaverine <=> ADP + phosphate + Glutathionylaminopropylcadaverine
|
6.3.1.9
trypanothione synthase
|
–
|
K
|
|
KEGG:
R08354
|
|
|
|
ATP + glutathione + Glutathionylaminopropylcadaverine <=> ADP + phosphate + Homotrypanothione
|
6.3.1.9
trypanothione synthase
|
–
|
K
|
|
KEGG:
R08355
|
|
|
|
R-CN + glutathione <=> cyanide + R-S-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
KEGG:
R08511
|
|
|
|
Sulfuric_monoester + glutathione <=> sulfate + R-S-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
KEGG:
R08512
|
|
|
|
15-Demethoxy-epsilon-rhodomycin + O2 + 2 glutathione <=> beta-Rhodomycin + CO2 + H2O + GSSG
|
not assigned
|
–
|
K
|
|
KEGG:
R09338
|
|
|
|
Selenodiglutathione + glutathione <=> Glutathioselenol + GSSG
|
not assigned
|
–
|
K
|
|
KEGG:
R09368
|
|
|
|
Aflatoxin_B1-exo-8,9-epoxide + glutathione <=> Aflatoxin_B1exo-8,9-epoxide-GSH
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R09409
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + reduced_flavodoxin + glutathione + O2 <=> S-[(E)-N-hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
KEGG:
R11734
|
|
|
|
Hepatotoxins + glutathione <=> R-S-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
K
|
|
KEGG:
R11905
|
|
|
|
xanthine_dehydrogenase + GSSG <=> xanthine_oxidase + glutathione
|
1.8.4.7
enzyme-thiol transhydrogenase (glutathione-disulfide)
|
–
|
|
|
MetaCyc:
1.8.4.7-RXN
|
|
|
|
S-adenosyl-L-methionine + arsenic_triglutathione + H2O + thioredoxin <=> dimethylarsinous_acid + S-adenosyl-L-homocysteine + glutathione + thioredoxin_disulfide
|
2.1.1.137
arsenite methyltransferase
|
–
|
M
|
|
MetaCyc:
2.1.1.137-RXN
|
|
|
|
[Glu(-Cys)]n+1-Gly + glutathione <=> [Glu(-Cys)]n+1-Gly + glycine
|
2.3.2.15
glutathione gamma-glutamylcysteinyltransferase
|
–
|
M
|
|
MetaCyc:
2.3.2.15-RXN
|
|
|
|
S-sulfocysteine + glutathione + H2O + acceptor <=> S-Glutathionyl-L-cysteine + sulfate + H+ + reduced_acceptor
|
not assigned
|
–
|
|
|
MetaCyc:
GSCYSSYN-RXN
|
|
|
|
glutathione + RX <=> R-S-glutathione + acceptor
|
2.5.1.18
glutathione transferase
|
–
|
M
|
|
MetaCyc:
GSHTRAN-RXN
|
|
|
|
glutathione + thioredoxin_disulfide <=> GSSG + reduced_glutaredoxin
|
not assigned
|
–
|
M
|
|
MetaCyc:
PRODISULFREDUCT-A-RXN
|
|
|
|
glutathione + a_protein_with_a_disulfide_bond <=> GSSG + a_protein_with_reduced_L-cysteine_residues
|
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
|
|
|
MetaCyc:
PRODISULFREDUCT-RXN
|
|
|
|
adenosine_5''-phosphosulfate + glutathione <=> H+ + AMP + S-Sulfoglutathione
|
2.8.2
|
–
|
|
|
MetaCyc:
R129-RXN
|
|
|
|
(2S)-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propan-1-one + glutathione <=> (2S)-2-(glutathion-S-yl)-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one + guaiacol
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-10902
|
|
|
|
(2R)-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propan-1-one + glutathione <=> (2R)-2-(glutathion-S-yl)-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one + guaiacol
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-10903
|
|
|
|
(2S)-2-(glutathion-S-yl)-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one + glutathione <=> 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one + GSSG
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-10904
|
|
|
|
(2R)-2-(glutathion-S-yl)-3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one + glutathione <=> 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one + GSSG
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-10905
|
|
|
|
a_1-aci-nitro-omega-(methylthio)alkane + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)pentan-1-imine + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11423
|
|
|
|
1-(methylsulfanyl)-6-aci-nitrohexane + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)hexan-1-imine + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11424
|
|
|
|
1-(methylsulfanyl)-7-aci-nitroheptane + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)heptan-1-imine + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11425
|
|
|
|
1-(methylsulfanyl)-8-aci-nitrooctane + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)octan-1-imine + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11426
|
|
|
|
1-(methylsulfanyl)-9-aci-nitrononane + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)nonan-1-imine + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11427
|
|
|
|
dehydro(indole-3-yl)acetonitrile + glutathione <=> (glutathion-S-yl)(1H-indol-3-yl)acetonitrile
|
2.5.1.18
glutathione transferase
|
–
|
M
|
|
MetaCyc:
RXN-11663
|
|
|
|
poly_gamma-glutamylcysteine-beta-alanine + glutathione <=> poly_gamma-glutamylcysteine-beta-alanine + glycine
|
2.3.2
|
–
|
M
|
|
MetaCyc:
RXN-12528
|
|
|
|
glutathione + gamma-L-glutamyl-L-cysteinyl-beta-alanine <=> gamma-Glu-Cys-gamma-Glu-Cys-beta-Ala + glycine
|
2.3.2
|
–
|
M
|
|
MetaCyc:
RXN-12529
|
|
|
|
Selenite + AMP + GSSG + H+ <=> adenosine_5''-phosphoselenate + glutathione
|
1.8.4.9
adenylyl-sulfate reductase (glutathione)
|
–
|
M
|
|
MetaCyc:
RXN-12721
|
|
|
|
Glutathioselenol + glutathione + NADP+ <=> Selenodiglutathione + NADPH + H+
|
1.8.1
|
–
|
M
|
|
MetaCyc:
RXN-12865
|
|
|
|
selenium + glutathione + NADP+ <=> Glutathioselenol + NADPH + H+
|
1.8.1
|
–
|
M
|
|
MetaCyc:
RXN-12867
|
|
|
|
S-sulfanylglutathione + glutathione <=> Sulfide + GSSG
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-15348
|
|
|
|
3-benzyl-3,6-dihydroxy-6-(hydroxymethyl)-diketopiperazine + glutathione <=> 3-benzyl-3,6_-bis(glutathione)-_6-(hydroxymethyl)-diketopiperazine + H2O
|
2.5.1.18
glutathione transferase
|
–
|
M
|
|
MetaCyc:
RXN-15680
|
|
|
|
glutathione + methacryloyl-CoA + H2O <=> 2-(glutathion-S-yl)-2-carboxypropane + CoA + H+
|
4.4.1
|
–
|
M
|
|
MetaCyc:
RXN-16193
|
|
|
|
glutathione + alkane <=> S-Methylglutathione + demethylated_methyl_donor
|
2.1.1
|
–
|
M
|
|
MetaCyc:
RXN-16203
|
|
|
|
2-(glutathione-S-yl)-2-methylbut-3-enoate + CoA + ATP + reduced_acceptor <=> 2-methyl-3-butenoyl-CoA + glutathione + ADP + phosphate + acceptor
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17595
|
|
|
|
S-(hydroxysulfenamide)glutathione + glutathione <=> GSSG + hydroxylamine
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17886
|
|
|
|
[protein]_3-nitrosothio-L-alanine + glutathione <=> protein + S-nitrosoglutathione
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-17887
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18158
|
|
|
|
(E)-phenylacetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> S-[(Z)-N-hydroxy(phenyl)acetimidoyl]-L-glutathione + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18159
|
|
|
|
4-methylthioheptanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)heptan-1-imine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18160
|
|
|
|
(E)-4-(methylsulfanyl)butanal_oxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18161
|
|
|
|
4-methylthiononanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)nonan-1-imine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18162
|
|
|
|
4-methylthiooctanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)octan-1-imine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18163
|
|
|
|
6-Methylthiohexanaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)hexan-1-imine + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18164
|
|
|
|
(E)-5-(methylsulfanyl)pentanal_oxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathion-S-yl)-N-hydroxy-omega-(methylsulfanyl)pentan-1-imine + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18165
|
|
|
|
1-(methylsulfanyl)-n-aci-nitroalkane + glutathione <=> (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-18170
|
|
|
|
omega-(methylthio)-(E)-alkanal_oxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> (E)-1-(glutathione-S-yl)-omega-(methylthio)alkylhydroximate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18171
|
|
|
|
tetrachlorohydroquinone + glutathione + H+ <=> 2-(glutathione-S-yl)-trichloro-p-hydroquinone + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
M
|
|
MetaCyc:
RXN-18405
|
|
|
|
2,3,5-trichlorohydroquinone + glutathione <=> 3-(glutathione-S-yl)-2,6-dichloro-p-hydroquinone + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
M
|
|
MetaCyc:
RXN-18407
|
|
|
|
deaminated_amino_group_donor + glutathione <=> aminated_amino_group_donor + N-(4-oxoglutaryl)-L-cysteinylglycine
|
2.6.1
|
–
|
|
|
MetaCyc:
RXN-18695
|
|
|
|
1-aci-nitro-2-(4-hydroxyphenyl)-ethane + glutathione <=> S-[(Z)-N-hydroxy(p-hydroxyphenyl)acetimidoyl]-L-glutathione + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18757
|
|
|
|
p-hydroxyphenylacetaldoxime + O2 + reduced_[NADPH-hemoprotein_reductase] + glutathione <=> S-[(Z)-N-hydroxy(p-hydroxyphenyl)acetimidoyl]-L-glutathione + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18758
|
|
|
|
glutathione + thiosulfate <=> S-sulfanylglutathione + sulfite + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19033
|
|
|
|
Sulfide + glutathione + electron-transfer_quinone <=> S-sulfanylglutathione + electron-transfer_quinol
|
1.8.5.8
eukaryotic sulfide quinone oxidoreductase
|
–
|
M
|
|
MetaCyc:
RXN-19036
|
|
|
|
S-sulfanylglutathione + sulfite + H+ <=> glutathione + thiosulfate
|
2.8.1.1
thiosulfate sulfurtransferase
|
–
|
M
|
|
MetaCyc:
RXN-19040
|
|
|
|
an_alkylcobalamin + glutathione + [cyanocobalamin_reductase_CblC] <=> cob(I)alamin-[cyanocobalamin_reductase_CblC] + an_S-alkylglutathione + H+
|
2.5.1.151
alkylcobalamin dealkylase
|
–
|
|
|
MetaCyc:
RXN-19370
|
|
|
|
glutathione + H2O <=> gamma-Glu-L-Cys + glycine
|
3.4.17.b
|
–
|
|
|
MetaCyc:
RXN-19585
|
|
|
|
glutathione + fenclorim <=> 4-(glutathion-S-yl)-fenclorim + Cl- + H+
|
2.5.1.18
glutathione transferase
|
–
|
|
|
MetaCyc:
RXN-19600
|
|
|
|
glutathione + methylmercury <=> methylmercury-S-glutatione + H+
|
2.5.1.18
glutathione transferase
|
–
|
|
|
MetaCyc:
RXN-19601
|
|
|
|
2-(glutathion-S-yl)-chloroacetate + H2O <=> glyoxylate + glutathione + Cl- + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19612
|
|
|
|
glutathione + (3Z)-hex-3-en-ol <=> 3-glutathionyl-hexan-1-ol
|
2.5.1.18
glutathione transferase
|
–
|
|
|
MetaCyc:
RXN-19626
|
|
|
|
glutathione + S-sulfocysteine <=> GSSG + L-cysteine + sulfite + H+
|
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
|
|
|
MetaCyc:
RXN-19629
|
|
|
|
S-adenosyl-L-methionine + glutathione <=> S-Methylglutathione + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
|
|
MetaCyc:
RXN-19922
|
|
|
|
[1-Cys-peroxiredoxin]-(glutathion-S-yl)-L-cysteine + glutathione <=> [1-Cys-peroxiredoxin]-L-cysteine + GSSG
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20696
|
|
|
|
[glutathione-S-transferase]-L-cysteine + glutathione + acceptor <=> [glutathione-S-transferase]-(glutathion-S-yl)-L-cysteine + reduced_acceptor
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20697
|
|
|
|
Polysulfide + GSSG <=> Polysulfide + S-sulfanylglutathione + glutathione
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20884
|
|
|
|
arsenite + glutathione <=> arsenic_triglutathione + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21019
|
|
|
|
thiarsahydroxy-[arsenate_reductase] + glutathione + H+ <=> S-glutathionyl-thiarsahydroxy-[arsenate_reductase] + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-21025
|
|
|
|
S-methyl-1-thio-D-xylulose_5-phosphate + glutathione <=> 1-deoxy-D-xylulose_5-phosphate + S-(methylsulfanyl)glutathione
|
2.8.4.e
|
–
|
M
|
|
MetaCyc:
RXN-21333
|
|
|
|
S-(methylsulfanyl)glutathione + glutathione <=> methanethiol + GSSG
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21334
|
|
|
|
(5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoic_acid + glutathione <=> 12(R)-HETE + GSSG + H2O
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-21584
|
|
|
|
glutathione + proteinogenic_amino_acid <=> gamma-glutamyl-L-alanine + Cys-Gly
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
M
|
|
MetaCyc:
RXN-6601
|
|
|
|
glutathione + intracellular_S0 <=> S-sulfanylglutathione
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8174
|
|
|
|
arsenate + glutathione + reduced_glutaredoxin + H+ <=> arsenite + [glutaredoxin]-glutathione_dithiol + H2O
|
1.20.4.1
arsenate reductase (glutathione/glutaredoxin)
|
–
|
M
|
|
MetaCyc:
RXN-982
|
|
|
|
6-(glutathion-S-yl)-2-methylhydroquinone + glutathione <=> toluquinol + GSSG
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
MetaCyc:
RXN0-7010
|
|
|
|
indole-3-methanol + glutathione <=> indol-3-ylmethyl-glutathione + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXNQT-4356
|
|
|
|
4-methoxyindol-3-ylmethyl_isothiocyanate + glutathione <=> (glutathion-S-yl)-4-methoxy-3-indolylmethylisothiocyanate
|
2.5.1
|
–
|
M
|
|
MetaCyc:
RXNQT-4361
|
|
|
|
indolyl-3-methyl-isothiocyanate + glutathione <=> indol-3-ylmethylisothiocyanate-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
M
|
|
MetaCyc:
RXNQT-4363
|
|
|
|
S-sulfanylglutathione + Fe3+ + H2O <=> H+ + sulfite + glutathione + Fe2+
|
not assigned
|
–
|
M
|
|
MetaCyc:
SULFFEOXIDO-RXN
|
|
|
|
sulfur + glutathione <=> S-sulfanylglutathione
|
not assigned
|
–
|
M
|
|
MetaCyc:
SULFUR-DIOXYGENASE-RXN
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + O2 + glutathione + reduced_flavodoxin <=> 1-aci-nitro-2-indolyl-ethane + H2O + flavin
|
1.14.14.43
(methylsulfanyl)alkanaldoxime N-monooxygenase
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
–
|
|
|
BRENDA:
BS439618
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime + reduced_flavodoxin + glutathione + O2 <=> S-[(E)-N-hydroxy(indol-3-yl)acetimidoyl]-L-glutathione + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BR52036
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + glutathione + O2 <=> S-[(Z)-N-hydroxy(p-hydroxyphenyl)acetimidoyl]-L-glutathione + flavin + 2 H2O
|
1.14.14.45
aromatic aldoxime N-monooxygenase
|
–
|
|
|
BRENDA:
BS438023
|
|
|
|
glutathione + O2 + O2 <=> GSSG + H2O
|
1.8.3.2
thiol oxidase
|
–
|
|
|
BRENDA:
BS259560
|
|
|
|
GTP + H2O + S-(2,4-dinitrophenyl)glutathione <=> GDP + phosphate + glutathione + 1,3-dinitrobenzene
|
7.4.2.10
ABC-type glutathione transporter
|
–
|
|
|
BRENDA:
BS447583
|
|
|
|
GTP + gamma-Glu-L-Cys + glycine <=> GDP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS560
|
|
|
|
Glyoxal + glutathione + NAD+ <=> S-oxoacetylglutathione + NADH
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS189074
|
|
|
|
farnesol + glutathione + NAD+ <=> S-farnesylglutathione + NADH
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS373191
|
|
|
|
12-hydroxydodecanoate + glutathione + NAD+ <=> S-(11-carboxy)undecanyl-glutathione + NADH + H+
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS371537
|
|
|
|
12-hydroxydodecanoate + glutathione + NAD+ <=> S-(11-carboxy)undecanylglutathione + NADH
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS371538
|
|
|
|
S-nitrosoglutathione + NADH <=> glutathione + NAD+ + NO
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS371156
|
|
|
|
hydroxypyruvaldehyde + glutathione + NAD+ <=> S-hydroxypyruvylglutathione + NADH
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS189075
|
|
|
|
3-ethoxy-2-hydroxybutyraldehyde + glutathione + NAD+ <=> S-(3-ethoxy-2-hydroxybutyryl)-glutathione + NADH + H+
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS189076
|
|
|
|
cinnamyl_alcohol + glutathione + NAD+ <=> S-cinnamylglutathione + NADH
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS372715
|
|
|
|
geraniol + glutathione + NAD+ <=> S-geranylglutathione + NADH
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS373275
|
|
|
|
glutathione + spermidine + MgATP2- <=> glutathionylspermidine + MgADP- + phosphate
|
6.3.1.8
glutathionylspermidine synthase
|
–
|
|
|
BRENDA:
BS369024
|
|
|
|
glutathione + 1-aminocyclopropane-1-carboxylate <=> Cys-Gly + 5-L-glutamyl-1-aminocyclopropane-1-carboxylic_acid
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321689
|
|
|
|
cis-1,2-dichlorooxirane + glutathione <=> 1,2-dichloro-2-(glutathion-S-yl)-ethan-1-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS436428
|
|
|
|
arsenate + glutathione + thioredoxin <=> arsenite + a_glutaredoxin-glutathione_disulfide + H2O
|
1.20.4.1
arsenate reductase (glutathione/glutaredoxin)
|
–
|
|
|
BRENDA:
BR47619
|
|
|
|
glutathione + daunorubicin <=> Cys-Gly + 5-L-glutamyl-daunomycin
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321688
|
|
|
|
coenzyme_M_disulfide + GSSG <=> 2 coenzyme_M + glutathione
|
1.8.1.8
protein-disulfide reductase
|
–
|
|
|
BRENDA:
BS441206
|
|
|
|
2-butyloxirane + glutathione <=> 2-(glutathion-S-yl)-hexan-1-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS436683
|
|
|
|
formaldehyde + glutathione + thio-NAD+ <=> S-formylglutathione + thio-NADH
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS189069
|
|
|
|
trans-1,2-dichloroepoxyethane + glutathione <=> 1,2-dichloro-2-(glutathion-S-yl)-ethan-1-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS436571
|
|
|
|
S-glyceroylglutathione + H2O <=> glycerate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS452607
|
|
|
|
S-L-glyceroylglutathione + H2O <=> glycerate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS452608
|
|
|
|
1,2-Epoxybutane + glutathione <=> 2-(glutathion-S-yl)-butan-1-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS436682
|
|
|
|
Epoxyethane + glutathione <=> 2-(glutathion-S-yl)-ethan-1-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS437531
|
|
|
|
glutathione + isodehydroascorbate <=> GSSG + isoascorbic_acid
|
1.8.5.1
glutathione dehydrogenase (ascorbate)
|
–
|
|
|
BRENDA:
BS260102
|
|
|
|
epithiopropane + glutathione <=> 2-(glutathion-S-yl)-propanthiol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS437530
|
|
|
|
glutathione + 2-(glutathione-S-yl)-methyl-p-hydroquinone <=> GSSG + methyl-p-hydroquinone
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BS439575
|
|
|
|
glutathione + 2-(glutathione-S-yl)-hydroxy-p-hydroquinone <=> GSSG + hydroxy-p-hydroquinone
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BS439571
|
|
|
|
glutathione + 2-(glutathione-S-yl)-1,4-benzoquinone <=> GSSG + 1,4-benzoquinone
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BS439569
|
|
|
|
glutathione + (glutathione-S-yl)-2-chloro-1,4-benzoquinone <=> GSSG + 2-chloro-1,4-benzoquinone
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BS439568
|
|
|
|
epichlorohydrin + glutathione <=> 3-chloro-2-(glutathion-S-yl)-propan-1-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS437528
|
|
|
|
glutathione + 2''-(glutathione-S-yl)-quercetin <=> GSSG + quercetin
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BS439576
|
|
|
|
an_alkylcobalamin + [alkylcobalamin_reductase] + glutathione <=> cob(I)alamin-[alkylcobalamin_reductase] + an_S-alkylglutathione
|
2.5.1.151
alkylcobalamin dealkylase
|
–
|
|
|
BRENDA:
BR52591
|
|
|
|
5-hydroperoxyeicosatetraenoic_acid + 2 glutathione <=> 5-hydroxyeicosatetraenoic_acid + GSSG + H2O
|
1.11.1.9
glutathione peroxidase
5.3.99.3
prostaglandin-E synthase
|
–
–
|
B
|
|
BRENDA:
BS261217
|
|
|
|
1-chloro-2,4-dinitrobenzene + glutathione <=> 2,4-dinitrobenzyl-glutathione + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS422254
|
|
|
|
1-chloro-2,4-dinitrobenzene + glutathione <=> S-(2,4-dinitrobenzyl)glutathione + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS446556
|
|
|
|
1-chloro-2,4-dinitrobenzene + glutathione <=> S-(2,3-dinitrophenyl)glutathione + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS378841
|
|
|
|
1-palmitoyl-2-(13-hydroperoxy-cis-9,trans-11-octadecadienoyl)-L-3-phosphatidylcholine + 2 glutathione <=> 1-palmitoyl-2-(13-hydroxy-cis-9,_trans-11-octadecadienoyl)-L-3-phosphatidylcholine + GSSG + H2O
|
1.11.1.9
glutathione peroxidase
|
–
|
|
|
BRENDA:
BS440513
|
|
|
|
glutathione + Cys-Gly <=> Cys-Gly + glutathione
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321666
|
|
|
|
leukotriene_A4_methyl_ester + glutathione <=> leukotriene_C4_methyl_ester + H2O
|
4.4.1.20
leukotriene-C4 synthase
|
–
|
|
|
BRENDA:
BS359191
|
|
|
|
NTP + GSSG <=> 2''-deoxyribonucleoside_triphosphate + glutathione + H2O
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
|
|
BRENDA:
BS287783
|
|
|
|
cis-2,3-Epoxybutane + glutathione <=> 3-(glutathion-S-yl)-butan-2-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS437282
|
|
|
|
4-(dimethylamino)-4''-azobenzene_thiosulfonate + glutathione <=> 4-(dimethylamino)-4''-azobenzene_sulfinate + glutathione
|
2.8.1.1
thiosulfate sulfurtransferase
|
–
|
|
|
BRENDA:
BS360019
|
|
|
|
5-Dimethylamino-1-naphthalene_thiosulfonate + glutathione <=> 5-Dimethylamino-1-naphthalene_sulfinate + glutathione
|
2.8.1.1
thiosulfate sulfurtransferase
|
–
|
|
|
BRENDA:
BS360022
|
|
|
|
S-mandeloylglutathione + H2O <=> Mandelate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS382778
|
|
|
|
cholesterol_7alpha-hydroperoxide + glutathione <=> 7alpha-hydroxycholesterol + GSSG
|
1.11.1.9
glutathione peroxidase
|
–
|
|
|
BRENDA:
BS261211
|
|
|
|
arsenate + glutathione <=> arsenite + GSSG + H2O
|
1.20.4.1
arsenate reductase (glutathione/glutaredoxin)
|
–
|
|
|
BRENDA:
BS443067
|
|
|
|
S-decyl-glutathione + H2O <=> Decanol + glutathione
|
3.4.19.14
leukotriene-C4 hydrolase
|
–
|
|
|
BRENDA:
BS419055
|
|
|
|
glutathione + Phenylglyoxal <=> S-mandeloylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS37505
|
|
|
|
(+/-)-2-bromo-3-(4-nitrophenyl)propionic_acid + glutathione <=> 2-(glutathion-S-yl)-3-(4-nitrophenyl)propanoic_acid
|
5.2.1.2
maleylacetoacetate isomerase
|
–
|
|
|
BRENDA:
BS368629
|
|
|
|
Sulfide + glutathione + coenzyme_Q10 <=> S-sulfanylglutathione + reduced_coenzyme_Q
|
1.8.5.8
eukaryotic sulfide quinone oxidoreductase
|
–
|
|
|
BRENDA:
BS443640
|
|
|
|
glutathione + methylglyoxal <=> S-Lactoylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS37509
|
|
|
|
GSSG + glutathione <=> GSSG + glutathione
|
1.8.4.4
glutathione---cystine transhydrogenase
|
–
|
|
|
BRENDA:
BS260613
|
|
|
|
methylcobalamin + [alkylcobalamin_reductase] + glutathione <=> cob(I)alamin-[alkylcobalamin_reductase] + S-Methylglutathione
|
2.5.1.151
alkylcobalamin dealkylase
|
–
|
|
|
BRENDA:
BS447790
|
|
|
|
S-nonylglutathione + H2O <=> 1-nonanol + glutathione
|
3.4.19.14
leukotriene-C4 hydrolase
|
–
|
|
|
BRENDA:
BS419062
|
|
|
|
propylene_oxide + glutathione <=> 2-(glutathion-S-yl)-propan-1-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS436467
|
|
|
|
cholesterol_5alpha-hydroperoxide + glutathione <=> 5alpha-hydroxycholesterol + GSSG
|
1.11.1.9
glutathione peroxidase
|
–
|
|
|
BRENDA:
BS261213
|
|
|
|
cholesterol_7beta-hydroperoxide + glutathione <=> 7beta-hydroxycholesterol + GSSG
|
1.11.1.9
glutathione peroxidase
|
–
|
|
|
BRENDA:
BS261212
|
|
|
|
glutathione + amino_acid <=> Cys-Gly + 5-L-glutamyl-L-amino_acid
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS370347
|
|
|
|
arsenate + glutathione <=> arsenite + glutathione
|
1.20.4.1
arsenate reductase (glutathione/glutaredoxin)
1.20.4.2
methylarsonate reductase
|
–
–
|
|
|
BRENDA:
BS189057
|
|
|
|
Harderoporphyrinogen + glutathione <=> harderoporphyrinogen-S-glutathione + H2O
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS421986
|
|
|
|
glutathione + ubiquinone <=> GSSG + ubiquinol
|
1.8.5.8
eukaryotic sulfide quinone oxidoreductase
|
–
|
|
|
BRENDA:
BS443609
|
|
|
|
glutathione + 4-nitrophenyl_acetate <=> S-(4-nitrophenyl)glutathione + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS409533
|
|
|
|
prostaglandin_G2 + glutathione <=> 15-hydroperoxy-prostaglandin_E2 + GSSG
|
5.3.99.3
prostaglandin-E synthase
|
–
|
|
|
BRENDA:
BS368752
|
|
|
|
epibromohydrine + glutathione <=> 3-bromo-2-(glutathion-S-yl)-propan-1-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS437527
|
|
|
|
S-butyrylglutathione + H2O <=> glutathione + Butyrate
|
3.1.2.7
glutathione thiolesterase
|
–
|
|
|
BRENDA:
BS382770
|
|
|
|
leukotriene_A4_free_acid + glutathione <=> leukotriene_C4
|
4.4.1.20
leukotriene-C4 synthase
|
–
|
|
|
BRENDA:
BS382211
|
|
|
|
cacodylate + glutathione <=> cacodylate
|
1.20.4.2
methylarsonate reductase
|
–
|
|
|
BRENDA:
BS189056
|
|
|
|
2-chloro-5-nitropyridine + glutathione <=> Cl- + L-gamma-glutamyl-S-(5-nitropyridin-2-yl)-L-cysteinylglycine
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS387117
|
|
|
|
methyl_3-(4-methoxyphenyl)oxirane-2-carboxylate + glutathione <=> Cl- + L-gamma-glutamyl-S-[2-hydroxy-3-methoxy-1-(4-methoxyphenyl)-3-oxopropyl]-L-cysteinylglycine
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS389163
|
|
|
|
7-oxabicyclo[4.1.0]heptan-2-one + glutathione <=> Cl- + L-gamma-glutamyl-S-(6-oxocyclohex-1-en-1-yl)-L-cysteinylglycine
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS387666
|
|
|
|
1-chloro-2,3-dinitrobenzene + glutathione <=> S-(2,3-dinitrophenyl)glutathione + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS378837
|
|
|
|
4-nitrophenyl_butyrate + glutathione <=> S-(4-nitrophenyl)glutathione + Butyrate
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS422630
|
|
|
|
6-pyruvoyltetrahydropterin + glutathione <=> pyrimidodiazepine
|
1.5.4.1
pyrimidodiazepine synthase
|
–
|
|
|
BRENDA:
BS287683
|
|
|
|
glutaryl-gamma-Glu-Cys-Gly + H2O <=> Glutarate + glutathione
|
3.5.1.93
glutaryl-7-aminocephalosporanic-acid acylase
|
–
|
|
|
BRENDA:
BS420724
|
|
|
|
methylarsonate + glutathione <=> methylarsonate + GSSG
|
1.20.4.2
methylarsonate reductase
|
–
|
|
|
BRENDA:
BS189055
|
|
|
|
5''-deoxyadenosylcobalamin + [alkylcobalamin_reductase] + glutathione <=> cob(I)alamin-[alkylcobalamin_reductase] + S-5''-deoxyadenosylglutathione
|
2.5.1.151
alkylcobalamin dealkylase
|
–
|
|
|
BRENDA:
BS446852
|
|
|
|
glutathione + 4-nitrobenzyl_chloride <=> Cl- + S-(4-nitrophenyl)glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388807
|
|
|
|
glutathione + 4-nitrobenzyl_chloride <=> Cl- + 4,4''-dichlorodiphenyltrichloroethane
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS437576
|
|
|
|
glutathione + 4-nitrobenzyl_chloride <=> S-(2,4-dinitrophenyl)glutathione + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS409531
|
|
|
|
glutathione + 4-nitrobenzyl_chloride <=> Cl- + S-(4-nitro-benzyl)glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388806
|
|
|
|
glutathione + Insulin <=> GSSG + reduced_insulin_chain_A_and_B
|
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
|
|
|
BRENDA:
BS260425
|
|
|
|
prostaglandin_H2 + 2 glutathione <=> Prostaglandin_D2 + GSSG + 2 H+
|
5.3.99.2
prostaglandin-D synthase
|
–
|
|
|
BRENDA:
BS370719
|
|
|
|
prostaglandin_H2 + glutathione <=> prostaglandin_E2 + GSSG
|
5.3.99.3
prostaglandin-E synthase
|
–
|
|
|
BRENDA:
BS368749
|
|
|
|
prostaglandin_H2 + glutathione <=> Prostaglandin_D2 + glutathione
|
5.3.99.2
prostaglandin-D synthase
|
–
|
|
|
BRENDA:
BS368738
|
|
|
|
insulin_disulfide + glutathione <=> Insulin + GSSG
|
1.8.4.9
adenylyl-sulfate reductase (glutathione)
|
–
|
|
|
BRENDA:
BS376991
|
|
|
|
insulin_disulfide + glutathione <=> Insulin_dithiol + GSSG
|
1.8.1.B5
|
–
|
|
|
BRENDA:
BS433845
|
|
|
|
glutathione + (2Z,4E)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic_acid <=> Cl- + 3-glutathionyl-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic_acid
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS386484
|
|
|
|
glutathione + (S)-2-amino-5-((R)-1-(carboxymethylamino)-3-(3-methyl-1,4-dioxo-1,4-dihydronaphthalen-2-ylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic_acid <=> GSSG + menadione
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BS439574
|
|
|
|
glutathione + (S)-2-amino-5-((R)-1-(carboxymethylamino)-3-(1,4-dihydroxy-3-methylnaphthalen-2-ylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic_acid <=> GSSG + menadione
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BS439573
|
|
|
|
glutathione + (S)-2-amino-5-((R)-1-(carboxymethylamino)-3-(1,4-dihydroxy-3-methylnaphthalen-2-ylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic_acid <=> GSSG + menadiol
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BS439572
|
|
|
|
insulin-(SS) + glutathione <=> Insulin-(SH)2 + GSSG
|
5.3.4.1
protein disulfide-isomerase
|
–
|
|
|
BRENDA:
BS1126
|
|
|
|
unfolded_insulin + glutathione <=> refolded_insulin + GSSG
|
5.3.4.1
protein disulfide-isomerase
|
–
|
|
|
BRENDA:
BS368708
|
|
|
|
unfolded_RNase_A + glutathione <=> refolded_RNase_A + GSSG
|
5.3.4.1
protein disulfide-isomerase
|
–
|
|
|
BRENDA:
BS368721
|
|
|
|
protoporphyrinogen-IX + glutathione <=> protoporphyrinogen-S-glutathione + H2O
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS422029
|
|
|
|
glutathione + phospholipid_hydroperoxide <=> GSSG + Phospholipid + H2O
|
1.11.1.12
phospholipid-hydroperoxide glutathione peroxidase
|
–
|
|
|
BRENDA:
BS451184
|
|
|
|
unfolded_bovine_pancreatic_ribonuclease_A + GSSG <=> refolded_bovine_pancreatic_ribonuclease_A + glutathione
|
5.3.4.1
protein disulfide-isomerase
|
–
|
|
|
BRENDA:
BS368704
|
|
|
|
denatured_RNase_A + glutathione <=> renatured_RNase_A + GSSG
|
5.3.4.1
protein disulfide-isomerase
|
–
|
|
|
BRENDA:
BS427426
|
|
|
|
S-D-mandeloylglutathione + H2O <=> (R)-mandelate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS417603
|
|
|
|
S-Lactoylglutathione + H2O <=> Lactone + glutathione
|
3.1.1.56
methylumbelliferyl-acetate deacetylase
|
–
|
|
|
BRENDA:
BS406625
|
|
|
|
GSSG + Reduced_ribonuclease <=> glutathione + oxidized_ribonuclease
|
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
|
|
|
BRENDA:
BS260431
|
|
|
|
oxidized_ribonucleotide_reductase + glutathione <=> reduced_ribonucleotide_reductase + GSSG
|
1.8.4.9
adenylyl-sulfate reductase (glutathione)
|
–
|
|
|
BRENDA:
BS377436
|
|
|
|
12-oxo-phytodienoic_acid + glutathione <=> 10-S-glutathionyl-12-oxo-phytodienoic_acid + H2O
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS421768
|
|
|
|
glutathione + acceptor <=> Cys-Gly + 5-L-Glutamyl-acceptor
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321663
|
|
|
|
L-Cystinyl-bis-glycine + glutathione <=> L-cystinyl-bis-Gly + GSSG
|
1.8.4.4
glutathione---cystine transhydrogenase
|
–
|
|
|
BRENDA:
BS260608
|
|
|
|
Sulfide + glutathione <=> sulfur + glutathione
|
1.8.5.4
bacterial sulfide:quinone reductase
|
–
|
|
|
BRENDA:
BS440404
|
|
|
|
S-m-nitrobenzyloxycarbonylglutathione + H2O <=> m-nitrobenzyloxycarboxylate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS93055
|
|
|
|
S-o-nitrobenzyloxycarbonylglutathione + H2O <=> o-nitrobenzyloxycarboxylate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS93054
|
|
|
|
reduced_denatured_RNase_A + glutathione <=> reduced_renatured_RNase_A + GSSG
|
5.3.4.1
protein disulfide-isomerase
|
–
|
|
|
BRENDA:
BS427521
|
|
|
|
epifluorohydrin + glutathione <=> 3-fluoro-2-(glutathion-S-yl)-propan-1-ol
|
4.4.1.34
isoprene-epoxide---glutathione S-transferase
|
–
|
|
|
BRENDA:
BS437529
|
|
|
|
ethyl_cobalamin + [alkylcobalamin_reductase] + glutathione <=> cob(I)alamin-[alkylcobalamin_reductase] + gamma-Glu-L-Cys(S-ethyl)-Gly
|
2.5.1.151
alkylcobalamin dealkylase
|
–
|
|
|
BRENDA:
BS447511
|
|
|
|
pantetheine-glutathione + glutathione <=> pantetheine + GSSG
|
1.8.4.3
glutathione---CoA-glutathione transhydrogenase
|
–
|
|
|
BRENDA:
BS260596
|
|
|
|
apocytochrome_c + GSSG <=> apocytochrome_c_disulfide + 2 glutathione
|
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
|
|
|
BRENDA:
BS441051
|
|
|
|
thiolethanolamine-glutathione + glutathione <=> cysteamine + GSSG
|
1.8.4.3
glutathione---CoA-glutathione transhydrogenase
|
–
|
|
|
BRENDA:
BS260597
|
|
|
|
propylcobalamin + [alkylcobalamin_reductase] + glutathione <=> cob(I)alamin-[alkylcobalamin_reductase] + gamma-Glu-L-Cys(S-propyl)-Gly
|
2.5.1.151
alkylcobalamin dealkylase
|
–
|
|
|
BRENDA:
BS448071
|
|
|
|
butyrylcobalamin + [alkylcobalamin_reductase] + glutathione <=> cob(I)alamin-[alkylcobalamin_reductase] + S-butyrylglutathione
|
2.5.1.151
alkylcobalamin dealkylase
|
–
|
|
|
BRENDA:
BS447254
|
|
|
|
hexylcobalamin + [alkylcobalamin_reductase] + glutathione <=> cob(I)alamin-[alkylcobalamin_reductase] + S-hexylglutathione
|
2.5.1.151
alkylcobalamin dealkylase
|
–
|
|
|
BRENDA:
BS447598
|
|
|
|
glutathione + leukotriene_D <=> Cys-Gly + leukotriene_C4
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321669
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid + glutathione <=> 15-hydroxyarachidonic_acid + GSSG
|
1.11.1.9
glutathione peroxidase
|
–
|
|
|
BRENDA:
BS261215
|
|
|
|
glutathione + 4-nitrophenyl_bromide <=> Br- + S-(4-nitrophenyl)glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388794
|
|
|
|
GSSG + reduced_alkaline_phosphatase <=> 2 glutathione + oxidized_alkaline_phosphatase
|
1.8.4.15
protein dithiol oxidoreductase (disulfide-forming)
|
–
|
|
|
BRENDA:
BS455753
|
|
|
|
5-Glutamyl-glutathione <=> 5-oxoproline + glutathione
|
4.3.2.9
gamma-glutamylcyclotransferase
|
–
|
|
|
BRENDA:
BS321724
|
|
|
|
Atrazine + glutathione <=> atrazine-S-glutathione + Cl-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS423055
|
|
|
|
glutathione + nitrobutyl_chloride <=> Cl- + nitrobutyl-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388819
|
|
|
|
4-nitrophenethyl_bromide + glutathione <=> S-(4-nitrophenyl)glutathione + Br-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS408130
|
|
|
|
glutathione + 4-nitrophenethyl_bromide <=> Br- + 4-nitrophenethyl-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388808
|
|
|
|
S-Lactoylglutathione + H2O <=> glutathione + Lactate
|
3.1.2.12
S-formylglutathione hydrolase
3.1.2.7
glutathione thiolesterase
|
–
–
|
|
|
BRENDA:
BS64591
|
|
|
|
glutathione + (2E,4Z)-5-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic_acid <=> Cl- + 5-glutathionyl-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic_acid
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS386483
|
|
|
|
glutathione + glutathione <=> Cys-Gly + 5-Glutamyl-glutathione
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321665
|
|
|
|
GSSG <=> glutathione
|
5.3.4.1
protein disulfide-isomerase
|
–
|
|
|
BRENDA:
BS379812
|
|
|
|
glutathione + iodobutane <=> I- + gamma-Glu-L-Cys(S-butyl)-Gly
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388796
|
|
|
|
glutathione + Iodoethane <=> I- + gamma-Glu-L-Cys(S-ethyl)-Gly
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388797
|
|
|
|
glutathione + Propyl_iodide <=> I- + gamma-Glu-L-Cys(S-propyl)-Gly
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388803
|
|
|
|
glutathione + iodohexane <=> I- + S-hexylglutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388799
|
|
|
|
glutathione + iodomethane <=> I- + S-Methylglutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388800
|
|
|
|
glutathione + 1-iodooctane <=> I- + octyl-S-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388801
|
|
|
|
glutathione + 1-iodo-3-phenylpropane <=> I- + 3-phenylpropyl-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388795
|
|
|
|
glutathione + 1-iodoheptane <=> I- + heptyl-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388798
|
|
|
|
glutathione + 1-iodopentane <=> I- + pentyl-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388802
|
|
|
|
5-L-glutamyl-4-nitroanilide + Cys-Gly <=> 4-nitroaniline + glutathione
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321667
|
|
|
|
N,S-bisfluorenylmethoxycarbonylglutathione + H2O <=> 9-fluorenylmethoxycarboxylate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS93053
|
|
|
|
S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione + H2O <=> N-hydroxy-N-bromophenylcarbamate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS93051
|
|
|
|
benzene_thiosulfonate + glutathione <=> more
|
2.8.1.3
thiosulfate---thiol sulfurtransferase
|
–
|
|
|
BRENDA:
BS360039
|
|
|
|
CTP + gamma-Glu-L-Cys + glycine <=> CDP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS559
|
|
|
|
Sulfide + glutathione + Ubiquinone-10 <=> S-sulfanylglutathione + coenzyme_Q10
|
1.8.5.8
eukaryotic sulfide quinone oxidoreductase
|
–
|
|
|
BRENDA:
BS443636
|
|
|
|
chanoclavine-I_aldehyde + glutathione + NADPH + H+ <=> agroclavine + GSSG + NADP+
|
1.5.1.46
agroclavine dehydrogenase
|
–
|
|
|
BRENDA:
BS423113
|
|
|
|
formaldehyde + glutathione + NADP+ <=> S-formylglutathione + NADPH + H+
|
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
|
–
|
|
|
BRENDA:
BS189063
|
|
|
|
glutathione-hydroxyethyl_disulfide + NADPH + H+ <=> glutathione + 2-sulfanylethan-1-ol + NADP+
|
1.8.1.B1
|
–
|
|
|
BRENDA:
BS441420
|
|
|
|
Sulfide + glutathione + ubiquinone <=> S-sulfanylglutathione + ubiquinol
|
1.8.5.4
bacterial sulfide:quinone reductase
1.8.5.8
eukaryotic sulfide quinone oxidoreductase
|
–
–
|
|
|
BRENDA:
BS437922
|
|
|
|
UTP + gamma-Glu-L-Cys + glycine <=> UDP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS558
|
|
|
|
glutathione + Glyoxal <=> S-glycolylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS37496
|
|
|
|
S-glycolylglutathione + H2O <=> glycolate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS93044
|
|
|
|
S-p-nitrobenzyloxycarbonylglutathione + H2O <=> p-nitrobenzyloxycarboxylate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS93056
|
|
|
|
3''-phosphoadenosine-5''-phosphosulfate + glutathione <=> adenosine_3'',5''-diphosphate + sulfite + GSSG
|
1.8.4.9
adenylyl-sulfate reductase (glutathione)
|
–
|
|
|
BRENDA:
BS189492
|
|
|
|
dATP + gamma-Glu-L-Cys + glycine <=> dADP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS557
|
|
|
|
ITP + gamma-Glu-L-Cys + glycine <=> IDP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS561
|
|
|
|
S-glycerylglutathione + H2O <=> glycerate + glutathione
|
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
|
|
|
BRENDA:
BS93043
|
|
|
|
cysteine-glutathione + glutathione <=> L-cysteine + GSSG
|
1.8.4.3
glutathione---CoA-glutathione transhydrogenase
|
–
|
|
|
BRENDA:
BS260598
|
|
|
|
glutathione + fenoxaprop <=> 4-hydroxyphenoxypropanoic_acid + glutathione_conjugate
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS354769
|
|
|
|
glutathione + 4-bromophenylglyoxal <=> S-(4-bromo)mandeloylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS453555
|
|
|
|
glutathione + 4-methylphenylglyoxal <=> S-(4-methyl)mandeloylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS453556
|
|
|
|
glutathione + fluorodifen <=> 4-nitrophenol + 2-nitro-4-trifluoromethylphenol-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS354770
|
|
|
|
glutathione + fluorodifen <=> 4-nitrophenol + (2-nitro-4-trifluoromethylphenyl)glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS397320
|
|
|
|
R-S-S-R + glutathione <=> glutathione-SSR + sulfhydryl_reagents
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS354741
|
|
|
|
[(methylamino)[methyl(nitroso)amino]methyl]cyanamide + glutathione <=> [bis(methylamino)methyl]cyanamide + S-nitrosoglutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS424373
|
|
|
|
S-nitrosoglutathione + H2O <=> nitrite + glutathione
|
3.4.19.14
leukotriene-C4 hydrolase
|
–
|
|
|
BRENDA:
BS419061
|
|
|
|
glutathione + 2,4-dimethylphenylglyoxal <=> S-(2,4-dimethyl)mandeloylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS37498
|
|
|
|
glutathione + m-methoxyphenylglyoxal <=> S-(3-methoxy)mandeloylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS37499
|
|
|
|
glutathione + p-chlorophenylglyoxal <=> S-(4-chloro)mandeloylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS37507
|
|
|
|
glutathione + p-hydroxyphenylglyoxal <=> S-(4-hydroxy)mandeloylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS37504
|
|
|
|
glutathione + p-methoxyphenylglyoxal <=> S-(4-methoxy)mandeloylglutathione
|
4.4.1.5
lactoylglutathione lyase
|
–
|
|
|
BRENDA:
BS37500
|
|
|
|
2 glutathione + spermidine + 2 ATP <=> trypanothione + 2 ADP + 2 phosphate
|
6.3.1.8
glutathionylspermidine synthase
6.3.1.9
trypanothione synthase
|
–
–
|
|
|
BRENDA:
BS378685
|
|
|
|
ATP + H2O + glutathione <=> ADP + phosphate + S-glutathione[side_2]
|
7.6.2.3
ABC-type glutathione-S-conjugate transporter
|
–
|
|
|
BRENDA:
BS445212
|
|
|
|
glutathione + glutathionylspermidine + ATP + H2O <=> N1,N8-bis-(gamma-L-Glu-L-Cys-Gly)-spermidine + ADP + phosphate + NH3
|
6.3.1.9
trypanothione synthase
|
–
|
|
|
BRENDA:
BS394
|
|
|
|
glutathione + spermidine + ATP <=> glutathionylspermidine + N8-glutathionylspermidine + ADP + phosphate
|
6.3.1.9
trypanothione synthase
|
–
|
|
|
BRENDA:
BS427453
|
|
|
|
peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + glutathione <=> peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + GSSG
|
1.8.98.2
sulfiredoxin
|
–
|
|
|
BRENDA:
BS398087
|
|
|
|
2-Cys_peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + glutathione <=> 2-Cys_peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + GSSG
|
1.8.98.2
sulfiredoxin
|
–
|
|
|
BRENDA:
BS440662
|
|
|
|
peroxiredoxin_IIF-(S-hydroxy-S-oxocysteine) + ATP + glutathione <=> peroxiredoxin_IIF-(S-hydroxycysteine) + ADP + phosphate + GSSG
|
1.8.98.2
sulfiredoxin
|
–
|
|
|
BRENDA:
BS441852
|
|
|
|
peroxiredoxin_III-(S-hydroxy-S-oxocysteine) + ATP + glutathione <=> peroxiredoxin_III-(S-hydroxycysteine) + ADP + phosphate + GSSG
|
1.8.98.2
sulfiredoxin
|
–
|
|
|
BRENDA:
BS441853
|
|
|
|
ATP + H2O + glutathione <=> ADP + phosphate + R-S-glutathione
|
7.6.2.3
ABC-type glutathione-S-conjugate transporter
|
–
|
|
|
BRENDA:
BS444225
|
|
|
|
ATP + H2O + glutathione-[trans-4-hydroxy-2-nonenal][side_1] <=> ADP + phosphate + glutathione + 4-hydroxy-2-nonenal
|
7.4.2.10
ABC-type glutathione transporter
|
–
|
|
|
BRENDA:
BS447045
|
|
|
|
ATP + H2O + glutathione + vincristine <=> ADP + phosphate + glutathione + vincristine
|
7.6.2.3
ABC-type glutathione-S-conjugate transporter
|
–
|
|
|
BRENDA:
BS445031
|
|
|
|
ATP + H2O + glutathione-[glutathione-binding_protein][side_1] <=> ADP + phosphate + glutathione + [glutathione-binding_protein][side_1]
|
7.4.2.10
ABC-type glutathione transporter
|
–
|
|
|
BRENDA:
BR52761
|
|
|
|
ATP + H2O + S-(2,4-dinitrophenyl)glutathione <=> ADP + phosphate + glutathione + 2,4-dinitrophenol[side_1]
|
7.4.2.10
ABC-type glutathione transporter
|
–
|
|
|
BRENDA:
BS447104
|
|
|
|
ATP + H2O + S-(2,4-dinitrophenyl)glutathione <=> ADP + phosphate + glutathione + 2,4-dinitrophenol
|
7.4.2.10
ABC-type glutathione transporter
|
–
|
|
|
BRENDA:
BS447103
|
|
|
|
ATP + H2O + S-(2,4-dinitrophenyl)glutathione <=> ADP + phosphate + glutathione + 1,3-dinitrobenzene
|
7.4.2.10
ABC-type glutathione transporter
|
–
|
|
|
BRENDA:
BS447106
|
|
|
|
ATP + Glu-L-2-aminobutyrate + glycine <=> ADP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS579
|
|
|
|
ATP + gamma-Glu-2-aminobutyrate + glycine <=> ADP + phosphate + glutathione
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS369128
|
|
|
|
glutathione + N8-Acetylspermidine + ATP <=> N1-glutathionyl-N8-acetylspermidine + ADP + phosphate
|
6.3.1.9
trypanothione synthase
|
–
|
|
|
BRENDA:
BS379808
|
|
|
|
7-Chloro-4-nitrobenzo-2-oxa-1,3-diazole + glutathione <=> 7-chloro-4-glutathionylbenzo-2-oxa-1,3-diazole
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS379076
|
|
|
|
L-methionine_(R)-S-oxide + glutathione <=> L-methionine + GSSG + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS426576
|
|
|
|
1,3,5-triacryloyl-1,3,5-triazinane + glutathione <=> L-gamma-glutamyl-S-[3-(3,5-diacryloyl-1,3,5-triazinan-1-yl)-3-oxopropyl]-L-cysteinylglycine
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS386952
|
|
|
|
heptyl-glutathione + H2O <=> 1-Heptanol + glutathione
|
3.4.19.14
leukotriene-C4 hydrolase
|
–
|
|
|
BRENDA:
BS419057
|
|
|
|
pentylcobalamin + [alkylcobalamin_reductase] + glutathione <=> cob(I)alamin-[alkylcobalamin_reductase] + pentyl-glutathione
|
2.5.1.151
alkylcobalamin dealkylase
|
–
|
|
|
BRENDA:
BS447975
|
|
|
|
L-Glu-4-nitroanilide + glutathione <=> 4-nitroaniline + 5-L-glutamyl-glutathione
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS370350
|
|
|
|
glutathione + ascorbate + O2 <=> gamma-Glu-Cys-NH2 + glyoxylate + dehydroascorbate + H2O
|
1.14.17.3
peptidylglycine monooxygenase
|
–
|
|
|
BRENDA:
BS375141
|
|
|
|
2,4,6-Trinitrobenzene + glutathione <=> S-(2,4,6-trinitrocyclohexa-2,5-dien-1-yl)glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS407705
|
|
|
|
brostallicin + glutathione <=> glutathionyl-brostallicin
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS407171
|
|
|
|
4-hydroxy-2-nonenal + glutathione <=> S-[(2S)-3-hydoxy-2-(2-oxoethyl)octyl]glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS410161
|
|
|
|
glutathione + (+)-anti-BPDE <=> Glutathione_conjugate_of_(+)-anti-BPDE
|
2.5.1.18
glutathione transferase
|
–
|
|
|
SABIO-RK:
7061
|
|
|
|
Benzyl_isothiocyanate + glutathione <=> S-(N-Benzylthiocarbamoyl)glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
SABIO-RK:
10319
|
|
|
|
GSSG + dihydrolipoamide <=> Lipoamide + 2 glutathione
|
not assigned
|
–
|
|
|
SABIO-RK:
13320
|
|